Human Sera
Cayman Chemical SarpogrelatehydrochlorIde 50mg
Source N-terminal His-tagged human STING R232 mutant from E. coli MW 28.8 kDa
Cayman Chemical 1PalmItoyl3LInolenoylrac 50mg
An anthelmintic has nematocidal activity against H. contortus (LD99 0.06 g/ml) and inhibits motility of adult worms (EC50 2 M) eliminates H. contortus T. colubriformis and O. ostertagi from experimentally infected jirds (ED95s 0.33 0.11 and 2.5 mg/animal respectively) dose-dependently inhibits nicotine-induced calcium mobilization in SH-SY5Y and TE-671 cells expressing a3 subunit-containing and muscle-type nAChRs respectively
Cayman Chemical SpIromesIfen 50mg
A bicyclic sesquiterpene a metabolite ofBcaryophyllene that has been found in C. sativa does not bind to the cannabinoid (CB) receptor CB2 (Ki 20 UM) induces calcium currents in HL-60 cells expressing CB2 receptors but also does so in CB2-deficient cells cytotoxic to HepG2 AGS HeLa SNU-1 and SNU-16 cells (IC50s 3.95 12.6 13.55 16.79 and 27.39 UM respectively) the volatile component of C. sativa sensed by narcotic detection dogs
Cayman Chemical PropargylcholInbromIde 50mg
An inhibitor of L-type calcium channels (IC50s 7.1 and 78.8 nM at -40 and -80 mV respectively in isolated guinea pig cardiomyocytes) preferentially inhibits L-type calcium channels in isolated rat portal vein over rat left ventricle (IC50s 427 and 20417 nM respectively) decreases mean arterial pressure in anesthetized normotensive or spontaneously hypertensive rats (ED30s 316 and 58 nmol/kg respectively)
Cayman Chemical FIlIpIn Complex 50mg
An analytical reference standard categorized as an opioid a known active metabolite of remifentanil intended for research and forensic applications
Cayman Chemical FludIoxonIl 100mg
An orally bioavailable dual inhibitor of Cdk4 and Cdk6 (IC50s 2 and 10 nM respectively) has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds
Cayman Chemical MyrIstoylLcarnItInchLRI 50mg
A C2 N-acyl homoserine lactone does not induce carbapenem antibiotic biosynthesis in E. carotovora does not induce fluorescence in E. coli containing a reporter plasmid of GFP in response to exogenous AHLs
Cayman Chemical ButyrylLcarnItInchLRIde 50mg
An inhibitor of Eg5 inhibits the basal and microtubule-stimulated states (IC50s 1000 and 140 nM respectively) selective over nine other human kinesins reversibly inhibits Eg5-driven microtubule sliding velocity (IC50 500 nM) induces cell cycle arrest in HeLa cells (IC50 700 nM) reversibly halts the cell cycle in the mitotic phase inhibits cancer cell growth in the NCI 60 human cancer cell line panel (average GI50 1.3 UM) and in mouse xenograft models
Cayman Chemical TrImethobenzamIDhydroCLOr 50mg
An antibiotic with diverse biological activites inhibits growth of S. aureus B. subtilis M. luteus M. flavus B. fragilis C. difficile C. perfringens and P. acnes (MICs 0.4-12.5 g/ml) inhibits strand-passing activity of topoisomerase II in a P4 unknotting assay inhibits protein synthesis in CEFs and 3T6 cells (IC50s 7 and 70 M respectively) cytotoxic to human lung carcinoma A549 cells in vitro (IC50 95 nM) increases median survival in P388 leukemia and B16 melanoma mouse tumor models (10 mg/kg per day)
Cayman Chemical TrIcosnoIc AcId 100mg
A major metabolite and degradation product of ciprofloxacin can be created through advanced oxygenation processes of ciprofloxacin in wastewater treatment can be created by chlorination of ciprofloxacin